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Have you had trouble making sense of recent trends in the drug supply and overdose rates? You’re not alone. In recent years, countless new synthetic drugs have entered the drug supply, and various theories are posited for changes in overdose death rates. On Monday, May 5, we heard from Dr. Nabarun Dasgupta, a scientist and activist at the University of North Carolina at Chapel Hill who focuses on overdose epidemiology and prevention. He explored why novel psychoactive substances and new markets have emerged in recent years and broke down recent overdose data trends and gaps. This Web Forum is sponsored by the National Overdose Prevention Network, a program of PHI Center for Health Leadership & Impact and produced by Dialogue4Health.